James Evan Wilson ,  M. He is played by Robert Sean Leonard. Gregory House. House's only true friend,  and frequently provides him with consultations and aid. House were originally supposed to play these roles; but Dr.
The Future is in your hands
"House" Don't Ever Change (TV Episode ) - Plot Summary - IMDb
Gregory House 's sole good friend up until his resignation from the hospital and probable, due to his refusal to continue treatment eventual death from Thymoma, which he was officially diagnosed with in the Season 8 episode, Body and Soul. He has been married and divorced three times his first wife was Sam Carr , the second wife was Bonnie Wilson , the third Julie Wilson. He has had a relationship with one of his terminally ill patients , and dated one of House's rejected applicants, Amber Volakis until her untimely death. Wilson states in Season 1 that he has no children. He does seem to suggest to last girlfriend Sam also his first wife that he wants a child with her in Season 7 , as when she says she should get a puppy, he replies, "Or pregnant. He has been treated for clinical depression.
Amber Volakis was one of the applicants for the fellowship positions that opened up in Season 4. She was first called by her assigned number, 24, and then later by her first name, she was usually referred to by Gregory House as "Cutthroat Bitch" due to her manipulative nature. She is portrayed by actress Anne Dudek.